Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy
Cancers | Free Full-Text | Drug Development Targeting the Ubiquitin–Proteasome System (UPS) for the Treatment of Human Cancers
Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells | Scientific Reports
Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1 - ScienceDirect
Continued ) F, schematic illustration of proposed mechanism underlying... | Download Scientific Diagram
Schema of the mechanism for MLN4924 enhancing ATRA-induced... | Download Scientific Diagram
Cancers | Free Full-Text | Targeting NEDDylation as a Novel Approach to Improve the Treatment of Head and Neck Cancer
Model for redox regulation of ENaC where reactive ROS or MLN4924... | Download Scientific Diagram
Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib
Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis | Cell Death & Disease
Frontiers | Neddylation: A Versatile Pathway Takes on Chronic Liver Diseases
Anticancer drug discovery by targeting cullin neddylation - ScienceDirect
Pevonedistat - an overview | ScienceDirect Topics
![PDF] The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/80cbd857543023682a105253c4bdb96a358339a4/4-Figure1-1.png "PDF] The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth. | Semantic Scholar")
PDF] The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth. | Semantic Scholar
Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells | Scientific Reports
Working model. Inhibition of neddylation pathway with MLN4924... | Download Scientific Diagram
IJMS | Free Full-Text | MLN4924, a Protein Neddylation Inhibitor, Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis
MLN4924 specifically inhibits neddylation and suppresses the growth of... | Download Scientific Diagram
Frontiers | Advances in Cancer Treatment by Targeting the Neddylation Pathway
Preclinical studies reveal MLN4924 is a promising new retinoblastoma therapy | Cell Death Discovery
Pevonedistat - an overview | ScienceDirect Topics
The NAE inhibitor pevonedistat (MLN4924) synergizes with TNF-α to activate apoptosis | Cell Death Discovery
