Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1 - Figure f8 | Aging
Cells | Free Full-Text | Calcium Pathways in Human Neutrophils—The Extended Effects of Thapsigargin and ML-9
Revealing Protein Aggregates under Thapsigargin-Induced ER Stress Using an ER-Targeted Thioflavin | ACS Sensors
Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress - ScienceDirect
Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation | Journal of Experimental & Clinical Cancer Research | Full Text
From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development | SpringerLink
The SERCA pump as a therapeutic target: Making a “smart bomb” for prostate cancer
Thapsigargin sensitizes human esophageal cancer to TRAIL-induced apoptosis via AMPK activation | Scientific Reports
Frontiers | Mechanism of Endoplasmic Reticulum Stress in Cerebral Ischemia
IJMS | Free Full-Text | Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in Carcinogenesis
Peptide–drug conjugate-based novel molecular drug delivery system in cancer: Trends in Pharmacological Sciences
Molecules | Free Full-Text | Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics
Chemical Specifications
Thapsigargin induces apoptosis when autophagy is inhibited in HepG2 cells and both processes are regulated by ROS-dependent pathway - ScienceDirect
IJMS | Free Full-Text | Thapsigargin—From Traditional Medicine to Anticancer Drug
MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System | eNeuro
Thapsigargin - Wikipedia
From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development | SpringerLink
Effect of endoplasmic reticulum calcium on paraquat‑induced apoptosis of human lung type II alveolar epithelial A549 cells
Endoplasmic reticulum stress signals in the tumour and its microenvironment | Nature Reviews Cancer
Autophagic degradation of stromal interaction molecule 2 mediates disruption of neuronal dendrites by endoplasmic reticulum stress - Zhou - 2019 - Journal of Neurochemistry - Wiley Online Library
Graphical Abstract
